Patent # RU 2146144 C1

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PREPARATION FOR PHOTODYNAMIC THERAPY
[11] Publication Number: 2146144
[13] Kind of Document: C1
[14] Publication Date: 2000.03.10
[19] Publishing Country or Organization: RU
[21] Appl. No.: 97102060/14
[22] Filled: 1997.02.11
[24] Effective Dates for Priority rights: 1997.02.11
[46] Claim(s) date: 2000.03.10
[51] Int. Cl.: A61K31/675, A61K31/40
[71] Applicant: Vorozhtsov G.N., Kogan E.A., Loshchenov V.B., Luk'janets E.A., Meerovich G.A., Torshina N.L., Juzhakova O.A.
[75] Inventors: Vorozhtsov G.N., Kogan E.A., Loshchenov V.B., Luk'janets E.A., Meerovich G.A., Torshina N.L., Juzhakova O.A.
[73] Assignee: Vorozhtsov G.N., Kogan E.A., Loshchenov V.B., Luk'janets E.A., Meerovich G.A., Torshina N.L., Juzhakova O.A.

[57] Abstract:

FIELD: medicine, oncology. SUBSTANCE: invention relates to preparations used for photodynamic therapy of patients with malignant neoplasms. Preparation for photodynamic therapy is phosphinemethyl derivatives of phthalocyanine of the general formula:PcM[CH2PO(OR)2]n where M is AlX, Zn, SnX2, SiX2, TiO; X is OH, OP(O)R(OR), Br or other halogen; R is H, C2H5 or other alkyl; n > 4 for Zn; n>=2 for tri- and tetravalent metals. Preparation exerts the greater deep effect on tissues. EFFECT: enhanced effectiveness of preparation as compared with known ones. 16 ex

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